Pfam Information-PF00027.18

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Pfam Header

IDENTIFICATION: cNMP_binding
DEFINITION: Cyclic nucleotide-binding domain
COMMENT:

Pfam Reference(s)

MEDLINE AUTHOR TITLE PUBLICATION COMMENT
94224763 Yau KW; Cyclic nucleotide-gated channels: an expanding new family of ion channels. Proc Natl Acad Sci USA 1994;91:3481-3483.

Family Structure

0....|....10...|....20...|....30...|....40...|....50...|....60...|....70...|....80...|....90...|....100..|....110..|....120..|....130..|....140..|....150..|....160..|....170..|....180..|....190..|....200..|....210..|....220..|....230..|....240..|....250..|....260..|....270..|....280..|....290..|....300..|....310..|....320..|....330..|....340..|....350..|....360..|.............
STRUCTURE EEEECT.TCE.E.E..CTTSC...CCEEEEEEESC..EEEEE.ECTTCEEEC.C.....................................................................................................................................................................................CEEEEEE.E.CTT.C..E.E.CHHHHHHCCCSS...................CCC-..-.-.-.....-.......S..SCCCSSEEEE...........SSSCEEE..EEE.EH.H..HHH.HH...HHHCHH
ACCESSIBILITY 435155.634.1.0..43547...15100001512..01122.556654452.9.....................................................................................................................................................................................4543324.0.352.2..1.0.113113374439...................474-..-.-.-.....-.......8..3150411020...........0336020..110.22.6..203.40...155145
CONSENSUS hpphtt.Gph.l.h..ppG-....ssphYllhpGp..lclht.pspssp..............................................................................................................................................................................................hth.l.ttG.s..h.h.G-hulhtsp....................................................pssslhA............hssspl..htl.sp.p..shp.pl...lpptsp

Co-evolving pairs with Z>=4 and Sequence Distance > 10

MUTATION COUNT COL 1 H1 COL 2 H2 H12 MI SEQUENCE DISTANCE AVG DISTANCE STDEV AVG RANDOM DISTANCE STDEV
547 257 3.502 317 3.861 6.87 0.493 18 5.7 1.7 17.6 6.4
646 24 3.795 317 3.677 6.988 0.484 55 3.7 0.8 23.3 10.1

Z>=4 average 3D distance: 4.7 stdev: 1.4

Co-evolving pairs with Z=3 and Sequence Distance > 10

MUTATION COUNT COL 1 H1 COL 2 H2 H12 MI SEQUENCE DISTANCE AVG DISTANCE STDEV AVG RANDOM DISTANCE STDEV
901 26 3.895 345 3.905 7.329 0.471 67 3.4 0.7 23.7 10
635 259 3.564 317 3.733 6.85 0.448 16 4.8 0.9 15.8 5.7
693 257 3.235 367 3.732 6.528 0.439 46 11.2 3.1 22 8.6
683 258 3.902 317 3.662 7.129 0.435 17 6 1.3 17.3 5.5
790 17 3.382 320 3.269 6.22 0.431 62 3.1 0.6 23.9 9.4
558 247 2.89 317 3.853 6.317 0.426 23 15.5 1.7 20.1 6
791 31 3.732 344 3.43 6.742 0.42 61 3.7 0.7 23.9 10.2

Z=3 average 3D distance: 6.8 stdev: 4.7

Download

Click to download File Size
MI: mi_pdb_PF00027.18_full_pfam.xml.gz 116 KB
Pfam: pdb_PF00027.18_full_pfam.xml.gz 134 KB

X3D PDB Models

The following X3D models currently only work with BS Contact for Windows. X3D is a new ISO standard and so not all VRML viewers have full support for the newer X3D features. Please see X3DPDB for additional information.

Click to download File Size
PDB: mi_pdb_PF00027.18_full_pfam_1j59_F.x3d 64 KB
PDB: mi_pdb_PF00027.18_full_pfam_1wgp_A.x3d 45 KB
PDB: mi_pdb_PF00027.18_full_pfam_1j59_E.x3d 64 KB
PDB: mi_pdb_PF00027.18_full_pfam_1rgs_A.x3d 84 KB
PDB: mi_pdb_PF00027.18_full_pfam_1ne4_A.x3d 85 KB
PDB: mi_pdb_PF00027.18_full_pfam_1i5z_B.x3d 66 KB
PDB: mi_pdb_PF00027.18_full_pfam_1i5z_A.x3d 64 KB
PDB: mi_pdb_PF00027.18_full_pfam_1o3r_E.x3d 65 KB
PDB: mi_pdb_PF00027.18_full_pfam_1ne6_A.x3d 85 KB
PDB: mi_pdb_PF00027.18_full_pfam_1rl3_B.x3d 82 KB
PDB: mi_pdb_PF00027.18_full_pfam_1rl3_A.x3d 85 KB
PDB: mi_pdb_PF00027.18_full_pfam_1o5l_A.x3d 43 KB


JSPWiki: PF00027.18
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